Member, WEI Executive Committee
Karen and William Monfre Professor of Chemical & Biological Engineering
College of Engineering
Jennifer Reed's group studies metabolism and regulation by combining computational and experimental approaches to study biological systems, engineer cells, and expand knowledge of the mechanisms underlying cellular behaviors. She studies microbes and microbial interactions involved in metabolic engineering, bioremediation and health applications. Her group's models enable the integration of diverse sets of experimental data to predict the structure and activity of cellular networks. Reed's research explores novel enzymes, reactions, and transcriptional and inter-species interactions to further elucidate genotype-phenotype relationships. She also works to quantify network activities using a variety of experimental (e.g., 13C metabolic flux analysis) and computational tools (e.g., constraint-based and kinetic models). Developed models allow her group to systematically evaluate the capabilities of different organisms from a network-based perspective and to identify ways in which genetic manipulations could enhance desired activities, such as chemical production.
- Systems biology
- Metabolic model development & analysis
- Metabolic engineering
- Biofuels, bioremediation & biotechnology